Dating Rare Mutations from Small Samples with Dense Marker Data
نویسندگان
چکیده
منابع مشابه
Dating rare mutations from small samples with dense marker data.
We present a method for estimating the age of a mutation based on the genetic length of ancestral haplotypes shared between individuals carrying the mutation. The method can be reliably applied to small samples, typical of situations involving rare mutations, and makes effective use of modern high-density SNP data, thus overcoming two of the limitations with existing methods. The method provide...
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ژورنال
عنوان ژورنال: Genetics
سال: 2014
ISSN: 1943-2631
DOI: 10.1534/genetics.114.164616